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Clinical Benefit of Cryoderm in Full Thickness Burns
Journal of Korean Burn Society 2012;15(2):121-126
Published online December 30, 2012
© 2012 대한화상학회지.

Young Min Kim, M.D., Hyeong Tae Yang, M.D., Hae Jun Lim, M.D., Dohern Kim, M.D., Jun Hur, M.D., Jong Hyun Kim, M.D., Yong Suk Cho, M.D. and Wook Chun, M.D.

Department of Burn Surgery, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea
Correspondence to: Wook Chun
Purpose: CryoDerm (CGbio) is derived donated human skin. After removing epidermis and fibroblast of dermal layer, it preserved with cryo-preservation technique using control rate freezer system. To prevent post burn joint contracture in massive burns, we have used CryoDerm in acute stage.
Methods: From January of 2010 to July of 2012, 50 patients who undergone CryoDerm graft with split thickness skin graft were reviewed. The operative method was as follows: 1) Early wound excision and or cadaveric allograft skin coverage was performed within 5 days after burn injury 2) 2∼3 weeks after wound excision, split thickness skin graft was performed with CryoDerm graft. Then graft take rate was investigated by inspection. Follow up duration was 3∼32 months.
Results: Mean age of patients was 42.2 (2∼70) years. Mean percentage of total body surface area burned was 27.22% (1∼61%). Among 50 patients, 98 joints was operated including 14 hands, 4 wrists, 10 shoulders, 23 elbows, 4 necks, 3 hip joints, 31 knee joints and 9 ankles and feet. Total used graft size of Cryoderm was 10,945 cm2. Average take rate was near 100%.
Conclusion: Cryoderm graft with split thickness skin graft can be used as a safe and effective operative method for one stage operation in acutely burned patients. (J Korean Burn Soc 2012;15:121-126)
Keywords : CryoDerm, CGbio, Artificial dermis, Full thickness burns

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