The Comparison of Blood Acid-Base Changes in Severe Burn Patients Resuscitation with Hart-mann Solution and Plasma Solution-A

Journal of Korean Burn Society 2015;18(1):7-12

Published online June 1, 2015

Sang Jin Lee, M.D., In Soo Cho, M.D., Young Tae Park, M.D., Young Min Jung, M.D., Soo Yerl Choi, M.D., Jin Heoung Park, M.D. and Kyung Tak Yoo, M.D.¹

Departments of Emergency Medicine, ¹Surgery, KEPCO Medical Center, Seoul, Korea

Correspondence to: In Soo Cho

Abstract: Purpose: Intravenous infusion of crystalloid solution is very important in the treatment of severe burn patients. But varia-ble blood acid-base differences can be induced due to crystalloids. The aim of this study was to compare, in severe burn patients, the effects of two balanced fluids (Hartmann solution and plasma solution-A) on blood chemical diffe-rences.Methods: A retrospective review was performed on 21 pa-tients from January 2010 to December 2012 who admitted as severe burn patients to KEPCO Medical Center burn care unit. One group was resuscitated with Hartmann solution ac-cording to Parkland formula. The other one was resuscitated with plasma solution-A.Results: 21 patients were enrolled. 14 patients belonged to plasma solution-A group and 7 patients belonged to Hart-mann solution group. Bicarbonate, pH, serum lactate and se-rum electrolytes showed no statistic differences between pla-sma solution-A and Hartmann solution group (P＞0.05). As time went by, pH and bicarbonate increased and serum lac-tate level decreased in both group.Conclusion: In this study, plasma solution-A had equally alka-linizing effect as Hartmann solution in severe burn patient resuscitation. (J Korean Burn Soc 2015;18:7-12); Keywords : Burn, Plasma solution-A, Hartmann solution, Metabolic acidosis

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