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The Clinical Investigation Study of Pancreatitis Developed in Burn Patients
Journal of Korean Burn Society 2019;22(1):10-14
Published online June 1, 2019
© 2019 Journal of Korean Burn Society.

Gi Yuon Cho, M.D., Jin Woo Chun, M.D.1, Young Min Kim, M.D.1, Jae Chul Yoon, M.D.1, Haejun Yim, M.D.1, Yong Suk Cho, M.D.1, Dohern Kim, M.D.1, Jun Hur, M.D.1 and Wook Chun, M.D.1

Department of Surgery, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, 1Department of Burn Surgery, Hangang Sacred Heart Hospital, Hallym University, Seoul, Korea
Correspondence to: 전 욱, 서울시 영등포구 버드나루로7길 12 ㉾ 07247, 한림대학교한강성심병원 화상외과
Tel: 02-2639-5001, Fax: 02-2633-7571
Received December 3, 2018; Revised January 3, 2019; Accepted January 17, 2019.
Purpose: To find progression and prognosis of pancreatitis developed in massive burn patients through retrospective analysis.
Methods: A retrospective study was conducted on 32 patients with abnormal increase of serum lipase level among 2523 acute burn patients admitted to our burn center from January 1, 2017 to June 30, 2018. Pancreatitis in this study was defined as a serum lipase concentration level that is higher than 180 IU/L which is three times more than the normal level (less than 60 IU/L). In this study, a retrospective analysis was performed on patients with serum lipase level higher than 300 IU/L to better understand causality of burns and pancreatitis.
Results: 32 patients (1.27%) had serum lipase level higher than 180 IU/L among 2523 acute burn subjects. And 13 patients (0.52%) of these 32 patients had serum lipase level elevated more than 300 IU/L. The study indicated serum lipase level was increased around 7 days after the injury. It returned to normal level early as after 1 to 2 weeks and late as after 4 to 6 weeks of injury. The serum amylase level was increased as similar modality as to the serum lipase level increase. The serum bilirubin, AST, ALT, LD, and GGT were also observed to be elevated when serum lipase was more than 1000 IU/L.
Conclusion: The pancreatitis developed in burn patients are mostly as mild symptom. It could due to the ischemic injury and can easily be treated by a temporary fasting, TPN, and Gabexate intravenous injection. 
Keywords : Pancreatitis, Burns

June 2019, 22 (1)
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