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Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns
Journal of Korean Burn Society 2019;22(2):45-48
Published online December 1, 2019
© 2019 Journal of Korean Burn Society.

Jangyoun Choi, M.D., Ph.D., Jin Tae Cho, M.D., Jong Yun Choi, M.D., Bommie Florence Seo, M.D., Ph.D. and Sung-No Jung, M.D., Ph.D.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea
Correspondence to: Sung-No Jung, Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 271 Chenbo-ro, Uijeongbu 11765, Korea
Tel: 82-31-820-3074, Fax: 82-31-874-0301
E-mail: jsn7190@catholic.ac.kr
Received October 17, 2019; Revised November 1, 2019; Accepted November 15, 2019.
Abstract
Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A geriatric patient visited our burn center showing second to third-degree burn on dorsum of her left hand. Considering the surface area and wound depth, surgery was indicated but her medical condition and age made the surgery high risk for a long operation. Therefore, chemical escharolysis, serial bedside debridement, and cultured allogenic keratinocyte (Kaloderm®, Tegoscience, Seoul, Korea) application was done. The wound was completely epithelialized after four rounds of Kaloderm® application. For third-degree burns where definitive surgical reconstruction is precluded due to medical comorbidity of the patient, we investigated the possibility of allogenic keratinocyte treatment which may allow to avoid high-risk anesthesia and surgery.
Keywords : Burn, Keratinocyte, Wound healing, Cell-and-tissue-based therapy


December 2019, 22 (2)
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