Guldem Turan, M.D., Funda Gumus Ozcan, M.D.1, Mustafa Turan, M.D.2, Birkan Bozkurt, M.D.2, Sibel Yurt, M.D.3, Ozlem Altuntas, M.D.4 and Nurettin Yiyit, M.D.5
University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of Intensive Care Unit, 1University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of Anesthesia and Reanimation, 2University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of General Surgery, 3University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of Chest Diseases, 4University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of Infection Diseases, 5University of Health Sciences Basaksehir Cam and Sakura City Hospital Department of Thoracic Surgery, Istanbul, Turkey
Correspondence to: Mustafa Turan, University of Health Sciences, Basaksehir Cam and Sakura City Hospital, Department of Burn Intensive Care Unit, Istanbul 34145, Turkey
Tel: +905427230535, Fax: +902129096000
E-mail: mturan9@gmail.com
Tel: +905427230535, Fax: +902129096000
E-mail: mturan9@gmail.com
Received May 27, 2024; Revised November 5, 2024; Accepted November 6, 2024.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Abstract
- In patients who have severe burn injuries with a large surface area, inflammatory response of the immune system, which is subsequently followed by anti-inflammatory response, results in immune dysregulation and this makes burn victims vulnerable to infection. With the disruption of skin integrity, the body becomes vulnerable to infection. Thermal injury disrupts cellular integrity, and eschar forms over the wound bed. Successive escharotomy procedures performed as part of treatment also lead to increased susceptibility to infection. The cytokine adsorber is a treatment modality that can be useful in preventing the transition to infection by removing inflammatory mediators from the blood. In our case series, we wanted to present the patients who were followed up for a prolonged period in our hospital’s burn intensive care clinic due to 75~90% 4th degree burns as a result of an explosion in a coal mine and periodically received cytokine adsorbents.
- Keywords : Sepsis, Cytokine adsorber, Burn, ICU
- December 2024, 27 (2)
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